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By Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson

Anesthesia and Analgesia in Laboratory Animals focuses solely at the precise anesthetic, analgesic, and postoperative care requisites linked to experimental surgical procedure. subsidized by way of the yankee collage of Laboratory Animal medication, this informative paintings presents the reader with brokers, equipment, and methods for anesthesia and analgesia that make sure humane and winning procedural results. Key good points* specializes in a large choice of animal species utilized in examine* offers a finished review of the pharmacology of anesthetics and analgesics* comprises tracking of analgesia and anesthesia* Organizes subject matters via species for brokers and techniques of offering anesthesia, analgesia, and post-op care to animals* No different American textual content is dedicated fullyyt to this subject

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1976). Cardiovascular effects of ketamine in the pithed rat, rabbit and cat. Br. J. Anaesth. 48, 935-939. Clark, S. , and Lipton, J. M. (1981). Effects of diazepam on body temperature of the aged squirrel monkey. Brain Res. Bull. 7, 5-9. Clemens, L. , Popham, T. , and Ruppert, P. H. (1979). Neonatal treatment of hamsters with barbiturate alters adult sexual behavior. Dev. Psychobiol. 12, 49-59. Cockshott, I. , Douglas E. , Plummer, G. E, and Simons, P. J. (1992). The pharmacokinetics of propofol in laboratory animals.

1974). , 1974), as well as in swine (Porter and Slusser, 1985). Its approved use in swine is to control aggressiveness and fighting (Booth, 1988c). In the rat, 90% of a radiolabeled azaperone dose is excreted within 48 hr. About 25% of the dose is recovered in the urine and the remainder in feces; 13% is excreted unchanged. , 1971). Azaperone administration to male mice and to rats of both sexes results in a transient elevation in the respiratory rate. In female mice, there is a progressive decline in respiration (Olson and Renchko, 1988).

1982). Effect of ketamine, althesin, and thiopentone on the valsalva-constrictor and heart rate reflexes of the rabbit. J. Auton. Nerv. Syst. 5, 291-301. Blake, D. , and McGrath, B. P. (1988). Haemodynamic and heart rate reflex responses to propofol in the rabbit. Br. J. Anaesth. 61, 194-199. Bogdan, L. , Glisson, S. , and E1-Etr, A. A. (1974). The effect of ketamine upon depolarizing and non-depolarizing neuromuscular blockade in rabbit. Naunyn-Schmiederberg 's Arch. Pharmacol. 285, 223-231. Booker, J.

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